World Antimicrobial Awareness Week

Antimicrobial Resistance (AMR) occurs when bacteria, viruses, fungi, and parasites no longer respond to antimicrobial agents. As a result of drug resistance, antibiotics and other antimicrobial agents become ineffective and infections become difficult or impossible to treat, increasing the risk of disease spread, severe illness, and death.

The World Antimicrobial Awareness Week (WAAW) is your chance to be part of a worldwide movement dedicated to combating this urgent crisis. WAAW, observed from November 18th to 24th every year, unites people to raise awareness about AMR and inspire action.

This year's theme emphasizes the importance of collaboration across sectors to safeguard the effectiveness of antimicrobials. It's a call to arms for individuals, communities, healthcare professionals, veterinarians, environmentalists, and policymakers to come together and embrace a shared responsibility. By working collectively, we can make a significant impact.

Here's how you can make a difference:

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  Use antimicrobials wisely and responsibly.

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  Take preventative measures to reduce infection rates.

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  Follow best practices for the disposal of antimicrobial-contaminated waste.

Join us in the fight against AMR during World Antimicrobial Awareness Week 2023. Together, we can protect our health, our planet, and the generations to come. Let's unite for a world free from the threat of drug-resistant infections.

Special Issues

Infection, Disease & Health

Special Issue on Antimicrobial Resistanceopens in new tab/window

Antimicrobial resistance (AMR) is global health threat. The causes and contributors to AMR vary, but include selective pressures by the overuse of antibiotics, genetic elements and substandard infection prevention and control practices. Infection Disease and Health is primarily concerned with the prevention and control of infections in human health. In this special issue of the journal, we have compiled a selection of articles that are related to one of the biggest challenges of our time – AMR. The articles included in this special issue include a broad range of topics, from antimicrobial stewardship, knowledge and attitudes towards antibiotics, prescribing practices and cost. Articles cover a diverse range of health settings, including hospitals, general practice and broader public health considerations. The special issue provides a great example of how the journal serves as an important platform for health research and uniquely contributes to the infection prevention and control agenda internationally.

International Journal of Infectious Diseases

AMR Collectionopens in new tab/window

Journal of Infection and Public Health

Special Issue on Antimicrobial Resistance, Stewardship and One Healthopens in new tab/window

Article collections

Cell Chemical Biology

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  Dual-pharmacophore artezomibs hijack the Plasmodium ubiquitin-proteasome system to kill malaria parasites while overcoming drug resistanceopens in new tab/window

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  Mitigating the risk of antimalarial resistance via covalent dual-subunit inhibition of the Plasmodium proteasomeopens in new tab/window

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  Selective killing of the human gastric pathogen Helicobacter pylori by mitochondrial respiratory complex I inhibitorsopens in new tab/window

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  Overcoming biological barriers to improve treatment of a Staphylococcus aureus wound infectionopens in new tab/window

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  Identification of triazenyl indoles as inhibitors of fungal fatty acid biosynthesis with broad-spectrum activityopens in new tab/window

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  Genome- and metabolome-guided discovery of marine BamA inhibitors revealed a dedicated darobactin halogenaseopens in new tab/window

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Cell Host & Microbe

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  Molecular de-extinction of ancient antimicrobial peptides enabled by machine learningopens in new tab/window

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  Multi-armed antibiotics for Gram-positive bacteriaopens in new tab/window

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  Pulsed antibiotic treatments of gnotobiotic mice manifest in complex bacterial community dynamics and resistance effectsopens in new tab/window

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  Long-term antibiotic exposure promotes mortality after systemic fungal infection by driving lymphocyte dysfunction and systemic escape of commensal bacteriaopens in new tab/window

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  The resistance within: Antibiotic disruption of the gut microbiome and resistome dynamics in infancyopens in new tab/window

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Clinical Infection in Practice

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  Impact of common comorbidities on antimicrobial consumption and mortality amongst critically ill COVID-19 patients: A retrospective two center study in Saudi Arabiaopens in new tab/window

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  A case of Extensively Drug Resistant (XDR) Extended Spectrum Beta-Lactamase (ESBL) typhoid fever in the Ambulatory Emergency Care (AEC) unitopens in new tab/window

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  Efficacy of convalescent plasma therapy in immunocompromised patients with COVID-19: A case reportopens in new tab/window

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  Pneumococcal prosthetic joint infection – A challenging diagnosisopens in new tab/window

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  Oral step-down for Staphylococcus aureus bacteraemia: An opportunity for antimicrobial stewardship?opens in new tab/window

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  Prescribing in a pandemic: Electronic prescribing aids to improve non-specialist adherence to COVID-19 guidelinesopens in new tab/window

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  Impact of common comorbidities on antimicrobial consumption and mortality amongst critically ill COVID-19 patients: A retrospective two center study in Saudi Arabiaopens in new tab/window

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  30 Determining a potential alternative empirical antibiotic regimen for the treatment of neonatal sepsis in low- and middle-income settings using pre-clinical in vitro techniquesopens in new tab/window

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  35 The clinical utility of microbiological culture and molecular testing of heart valves in surgically treated infective endocarditisopens in new tab/window

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Clinical Microbiology and Infection

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  European Society of Clinical Microbiology and Infectious Diseases (ESCMID) guidelines for the treatment of infections caused by multidrug-resistant Gram-negative bacilli (endorsed by European society of intensive care medicine)opens in new tab/window

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  Colonization by ceftazidime/avibactam-resistant KPC-producing Klebsiella pneumoniae following therapy in critically ill patientsopens in new tab/window

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  ESCMID/EUCIC clinical practice guidelines on perioperative antibiotic prophylaxis in patients colonized by multidrug-resistant Gram-negative bacteria before surgeryopens in new tab/window

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  Antibiotic heteroresistance in ESKAPE pathogens, from bench to bedsideopens in new tab/window

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  Impact of antibiotic intake on the incidence of extended-spectrum β-lactamase–producing Enterobacterales in sub-Saharan Africa: results from a community-based longitudinal studyopens in new tab/window

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  Real-world clinical outcome of cefiderocol for treatment of multidrug-resistant non-fermenting, gram negative bacilli infections: a case seriesopens in new tab/window

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  Macrolide therapy in Pseudomonas aeruginosa infections causes uL4 ribosomal protein mutations leading to high-level resistanceopens in new tab/window

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  The emergence of a multidrug resistant Salmonella Muenchen in Israel is associated with horizontal acquisition of the epidemic pESI plasmidopens in new tab/window

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  Clinical consequences of very major errors with semi-automated testing systems for antimicrobial susceptibility of carbapenem-resistant Enterobacteralesopens in new tab/window

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  IDSA guidance and ESCMID guidelines: complementary approaches toward a care standard for MDR Gram-negative infectionsopens in new tab/window

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  How I manage a patient with MRSA bacteraemiaopens in new tab/window

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  How to: screening for mcr-mediated resistance to colistinopens in new tab/window

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Current Opinion in Microbiology

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  Nothing makes sense in drug resistance except in the light of evolutionopens in new tab/window

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  Interplay of emerging and established technologies drives innovation in natural product antibiotic discoveryopens in new tab/window

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  Present and future outlooks on environmental DNA-based methods for antibiotic discoveryopens in new tab/window

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Epidemics

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  Linking antimicrobial prescribing to antimicrobial resistance in the ICU: Before and after an antimicrobial stewardship programopens in new tab/window

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  Transmission dynamics of an antimicrobial resistant Campylobacter jejuni lineage in New Zealand’s commercial poultry networkopens in new tab/window

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Food Microbiology

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  Determination and quantification of microbial communities and antimicrobial resistance on food through host DNA-depleted metagenomicsopens in new tab/window

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  A five-year study on prevalence and antimicrobial resistance of Campylobacter from poultry carcasses in Polandopens in new tab/window

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  Combined metabolomics and transcriptomics analysis reveals the mechanism of antibiotic resistance of Salmonella enterica serovar Typhimurium after acidic stressopens in new tab/window

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Infection Prevention in Practice

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  Management of BAME patients with a history of penicillin allergy: barriers to best practice and strategies to overcome these - ScienceDirectopens in new tab/window

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  World Antimicrobial Resistance Awareness Week 2023: the overlooked challenges of antimicrobial stewardship - ScienceDirect

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  Challenges of implementing antimicrobial stewardship tools in Low to Middle Income Countries (LMICs) - ScienceDirectopens in new tab/window

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  Antimicrobial resistance as a super wicked problem: how do we engage the public to be part of the solution - ScienceDirectopens in new tab/window

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International Journal of Antimicrobial Agents

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  Reducing the duration of antibiotic therapy in surgical patients through a specific nationwide antimicrobial stewardship program. A prospective, interventional cohort studyopens in new tab/window

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  Changes in the prevalence of pathogens causing hospital-acquired bacterial pneumonia and the impact of their antimicrobial resistance patterns on clinical outcomes: A propensity-score-matched studyopens in new tab/window

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  Effect of a national antibiotic stewardship intervention in China targeting carbapenem overuse: An interrupted time-series analysisopens in new tab/window

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  Antimicrobial resistance surveillance: China's nearly 40-year effortopens in new tab/window

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  The battle against fungi: lessons in antifungal stewardship from COVID 19 timesopens in new tab/window

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  Prescription of antibiotics by general practitioners for patients with a diagnosis of SARS- CoV-2 infection: Analysis of an electronic French health recordopens in new tab/window

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  Multidrug-resistant Gram-negative bacilli recovered from respiratory and blood specimens from adults: the ATLAS surveillance program in European hospitals, 2018–2020opens in new tab/window

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  Geographic patterns of carbapenem-resistant, multi-drug-resistant and difficult-to-treat Acinetobacter baumannii in the Asia-Pacific region: results from the Antimicrobial Testing Leadership and Surveillance (ATLAS) program, 2020opens in new tab/window

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  Long-term follow-up of HIV-1 multi-drug-resistant treatment-experienced participants treated with etravirine, raltegravir and boosted darunavir: towards drug-reduced regimen? ANRS CO3 Aquitaine Cohort 2007–2018opens in new tab/window

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International Journal of Infectious Diseases

Editorial

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  Antimicrobial resistance – a global problem in need of global solutionsopens in new tab/window

Research articles

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  Indications and classes of outpatient antibiotic prescriptions in Japan: A descriptive study using the national database of electronic health insurance claims, 2012–2015opens in new tab/window

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  Antibiotic use in Kenyan public hospitals: Prevalence, appropriateness and link to guideline availabilityopens in new tab/window

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  Surgical site infections after pancreaticoduodenectomy: Preoperative biliary system interventions and antimicrobial prophylaxisopens in new tab/window

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  Effectiveness of ceftazidime–avibactam versus colistin in treating carbapenem-resistant Enterobacteriaceae bacteremiaopens in new tab/window

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  Emergence of clinical isolates of highly carbapenem-resistant Klebsiella pneumoniae co-harboring blaNDM-5 and blaOXA-181 or -232 in Nepalopens in new tab/window

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  In vitro efficacy of ceftazidime-avibactam, aztreonam-avibactam and other rescue antibiotics against carbapenem-resistant Enterobacterales from the Arabian Peninsulaopens in new tab/window

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  Value of routine whole genome sequencing for Mycobacterium tuberculosis drug resistance detectionopens in new tab/window

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  High prevalence of ESBL-producing Klebsiella pneumoniae in clinical samples from central Côte d'Ivoireopens in new tab/window

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  Clonal expansion of colistin-resistant Acinetobacter baumannii isolates in Cape Town, South Africaopens in new tab/window

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  Molecular epidemiology of Carbapenem-resistant Klebsiella pneumoniae in a paediatric hospital in Chinaopens in new tab/window

Review

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  Global Antimicrobial Stewardship with a Focus on Low- and Middle-Income Countriesopens in new tab/window

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  Impact of vaccines on antimicrobial resistanceopens in new tab/window

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  COVID-19 and antimicrobial stewardship: lessons learned, best practices, and future implicationsopens in new tab/window

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  Global knowledge gaps on antimicrobial resistance in the human health sector: A scoping reviewopens in new tab/window

Perspectives

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  Antibiotics and antimicrobial resistance in the COVID-19 era: Perspective from resource-limited settingsopens in new tab/window

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iScience

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  Synthetic antibacterial discovery of symbah-1, a macrocyclic β-hairpin peptide antibioticopens in new tab/window

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  A history of the MetaSUB consortium: Tracking urban microbes around the globeopens in new tab/window

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  Metagenomic analysis reveals the dissemination mechanisms and risks of resistance genes in plateau lakesopens in new tab/window

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  Bacterial memory in antibiotic resistance evolution and nanotechnology in evolutionary biologyopens in new tab/window

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  Characterization of a novel genus of jumbo phages and their application in wastewater treatmentopens in new tab/window

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Journal of Global Antimicrobial Resistance

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  Nosocomial Outbreak of Colistin-Resistant, Carbapenemase-Producing Klebsiella Pneumoniae ST11 in a Medical Intensive Care Unitopens in new tab/window

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  Impact of antimicrobial stewardship 2018 on severe pneumonia with bacterial infection in PICUopens in new tab/window

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  Emergence of optrA-mediated linezolid resistance in clinical isolates of Enterococcus faecalis from Argentinaopens in new tab/window

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  Comparison of ANN and LR models for predicting Carbapenem-resistant Klebsiella pneumoniae isolates from a southern province of China's RNSS dataopens in new tab/window

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  Prevalence of antibiotic resistance of Staphylococcus aureus in cystic fibrosis infection: A systematic review and meta-analysisopens in new tab/window

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  Epidemiology of staphylococci species and their antimicrobial-resistance among patients with wound infection in Ethiopia: a systematic review and meta-analysisopens in new tab/window

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Journal of Hospital Infection

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  Impact of Intensified Inpatient Clindamycin Stewardship Initiatives in Three Phases: A Pilot Quasi-Experimental Studyopens in new tab/window

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  The cost-effectiveness of a real-time spatiotemporal mapping surveillance system for meticillin-resistant Staphylococcus aureus preventionopens in new tab/window

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  Virulence genes and plasmid replicon profiles of selected β-lactamase-producing Acinetobacter baumannii from orthopaedic patients and the environment in a tertiary referral hospital in Tanzania, East Africaopens in new tab/window

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  Swimming pool policies for carriers of highly-resistant micro-organisms receiving rehabilitation care in the Netherlandsopens in new tab/window

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  Wastewater-based epidemiology for tracking bacterial diversity and antibiotic resistance in COVID-19 isolation hospitals in Qataropens in new tab/window

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  Qualitative analysis of healthcare provider perspectives to evaluating beta-lactam allergiesopens in new tab/window

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  Modelling hospital disinfectant against multi-drug-resistant dry surface biofilms grown under artificial human sweatopens in new tab/window

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  Analysis of carbapenem-resistant strains isolated in a tertiary care hospital in Rawalpindi, Pakistan, during the years 2016 and 2020opens in new tab/window

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Journal of Microbiological Methods

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  Evaluation of metagenomic assembly methods for the detection and characterization of antimicrobial resistance determinants and associated mobilizable elementsopens in new tab/window

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  A rapid MALDI-TOF mass spectrometry-based method for categorization of Pseudomonas aeruginosa from blood cultures as susceptible or resistant to meropenemopens in new tab/window

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  Comparison of FT-IR with whole-genome sequencing for identification of maternal-to‑neonate transmission of antibiotic-resistant bacteriaopens in new tab/window

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Med

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  Refractory Pseudomonas aeruginosa infections treated with phage PASA16: A compassionate use case seriesopens in new tab/window

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Microbes and Infection

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  Nanomotion technology in combination with machine learning: a new approach for a rapid antibiotic susceptibility test for Mycobacterium tuberculosisopens in new tab/window

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  Therapeutic potential of kaempferol on Streptococcus pneumoniae infectionopens in new tab/window

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  Crystal violet decolorization assay: a simplified colorimetric test for the rapid detection of multidrug-resistant Mycobacterium tuberculosis isolatesopens in new tab/window

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Microbial Risk Analysis

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  Estimating the likelihood of ESBL-producing E. coli carriage in slaughter-aged pigs following bacterial introduction onto a farm: A multiscale risk assessmentopens in new tab/window

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  Multidirectional dynamic model for the spread of extended-spectrum-B-lactamase-producing Escherichia coli in the Netherlandsopens in new tab/window

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Microbiological Research

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  The menace of colistin resistance across globe: Obstacles and opportunities in curbing its spreadopens in new tab/window

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  Genomic insight into the distribution and genetic environment of blaIMP-4 in clinical carbapenem-resistant Klebsiella pneumoniae strains in Chinaopens in new tab/window

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Research in Microbiology

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  Analysis of AcrB in Klebsiella pneumoniae reveals natural variants promoting enhanced multidrug resistanceopens in new tab/window

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  Vancomycin-resistant Enterococcus faecium and the emergence of new sequence types associated with hospital infectionopens in new tab/window

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  Bacteriophages potentiate the effect of antibiotics by eradication of persister cells and killing of biofilm-forming cells(opens in new tab/window)opens in new tab/window

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  Transcription factor mce3R modulates antibiotics and disease persistence in Mycobacterium tuberculosisopens in new tab/window

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LabLinks: Antimicrobial resistance