World Antimicrobial Awareness Week

Antimicrobial Resistance (AMR) occurs when bacteria, viruses, fungi, and parasites no longer respond to antimicrobial agents. As a result of drug resistance, antibiotics and other antimicrobial agents become ineffective and infections become difficult or impossible to treat, increasing the risk of disease spread, severe illness, and death.

The World Antimicrobial Awareness Week (WAAW) is your chance to be part of a worldwide movement dedicated to combating this urgent crisis. WAAW, observed from November 18th to 24th every year, unites people to raise awareness about AMR and inspire action.

This year's theme emphasizes the importance of collaboration across sectors to safeguard the effectiveness of antimicrobials. It's a call to arms for individuals, communities, healthcare professionals, veterinarians, environmentalists, and policymakers to come together and embrace a shared responsibility. By working collectively, we can make a significant impact.

Here's how you can make a difference:

• Use antimicrobials wisely and responsibly.

• Take preventative measures to reduce infection rates.

• Follow best practices for the disposal of antimicrobial-contaminated waste.

Join us in the fight against AMR during World Antimicrobial Awareness Week 2023. Together, we can protect our health, our planet, and the generations to come. Let's unite for a world free from the threat of drug-resistant infections.

Special Issues

Infection, Disease & Health

Special Issue on Antimicrobial Resistance se abre en una nueva pestaña/ventana

Antimicrobial resistance (AMR) is global health threat. The causes and contributors to AMR vary, but include selective pressures by the overuse of antibiotics, genetic elements and substandard infection prevention and control practices. Infection Disease and Health is primarily concerned with the prevention and control of infections in human health. In this special issue of the journal, we have compiled a selection of articles that are related to one of the biggest challenges of our time – AMR. The articles included in this special issue include a broad range of topics, from antimicrobial stewardship, knowledge and attitudes towards antibiotics, prescribing practices and cost. Articles cover a diverse range of health settings, including hospitals, general practice and broader public health considerations. The special issue provides a great example of how the journal serves as an important platform for health research and uniquely contributes to the infection prevention and control agenda internationally.

International Journal of Infectious Diseases

AMR Collection se abre en una nueva pestaña/ventana

Journal of Infection and Public Health

Special Issue on Antimicrobial Resistance, Stewardship and One Health se abre en una nueva pestaña/ventana

Article collections

Cell Chemical Biology

• Dual-pharmacophore artezomibs hijack the Plasmodium ubiquitin-proteasome system to kill malaria parasites while overcoming drug resistance se abre en una nueva pestaña/ventana

• Mitigating the risk of antimalarial resistance via covalent dual-subunit inhibition of the Plasmodium proteasome se abre en una nueva pestaña/ventana

• Selective killing of the human gastric pathogen Helicobacter pylori by mitochondrial respiratory complex I inhibitors se abre en una nueva pestaña/ventana

• Overcoming biological barriers to improve treatment of a Staphylococcus aureus wound infection se abre en una nueva pestaña/ventana

• Identification of triazenyl indoles as inhibitors of fungal fatty acid biosynthesis with broad-spectrum activity se abre en una nueva pestaña/ventana

• Genome- and metabolome-guided discovery of marine BamA inhibitors revealed a dedicated darobactin halogenase se abre en una nueva pestaña/ventana

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Cell Host & Microbe

• Molecular de-extinction of ancient antimicrobial peptides enabled by machine learning se abre en una nueva pestaña/ventana

• Multi-armed antibiotics for Gram-positive bacteria se abre en una nueva pestaña/ventana

• Pulsed antibiotic treatments of gnotobiotic mice manifest in complex bacterial community dynamics and resistance effects se abre en una nueva pestaña/ventana

• Long-term antibiotic exposure promotes mortality after systemic fungal infection by driving lymphocyte dysfunction and systemic escape of commensal bacteria se abre en una nueva pestaña/ventana

• The resistance within: Antibiotic disruption of the gut microbiome and resistome dynamics in infancy se abre en una nueva pestaña/ventana

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Clinical Infection in Practice

• Impact of common comorbidities on antimicrobial consumption and mortality amongst critically ill COVID-19 patients: A retrospective two center study in Saudi Arabia se abre en una nueva pestaña/ventana

• A case of Extensively Drug Resistant (XDR) Extended Spectrum Beta-Lactamase (ESBL) typhoid fever in the Ambulatory Emergency Care (AEC) unit se abre en una nueva pestaña/ventana

• Efficacy of convalescent plasma therapy in immunocompromised patients with COVID-19: A case report se abre en una nueva pestaña/ventana

• Pneumococcal prosthetic joint infection – A challenging diagnosis se abre en una nueva pestaña/ventana

• Oral step-down for Staphylococcus aureus bacteraemia: An opportunity for antimicrobial stewardship? se abre en una nueva pestaña/ventana

• Prescribing in a pandemic: Electronic prescribing aids to improve non-specialist adherence to COVID-19 guidelines se abre en una nueva pestaña/ventana

• Impact of common comorbidities on antimicrobial consumption and mortality amongst critically ill COVID-19 patients: A retrospective two center study in Saudi Arabia se abre en una nueva pestaña/ventana

• 30 Determining a potential alternative empirical antibiotic regimen for the treatment of neonatal sepsis in low- and middle-income settings using pre-clinical in vitro techniques se abre en una nueva pestaña/ventana

• 35 The clinical utility of microbiological culture and molecular testing of heart valves in surgically treated infective endocarditis se abre en una nueva pestaña/ventana

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Clinical Microbiology and Infection

• European Society of Clinical Microbiology and Infectious Diseases (ESCMID) guidelines for the treatment of infections caused by multidrug-resistant Gram-negative bacilli (endorsed by European society of intensive care medicine) se abre en una nueva pestaña/ventana

• Colonization by ceftazidime/avibactam-resistant KPC-producing Klebsiella pneumoniae following therapy in critically ill patients se abre en una nueva pestaña/ventana

• ESCMID/EUCIC clinical practice guidelines on perioperative antibiotic prophylaxis in patients colonized by multidrug-resistant Gram-negative bacteria before surgery se abre en una nueva pestaña/ventana

• Antibiotic heteroresistance in ESKAPE pathogens, from bench to bedside se abre en una nueva pestaña/ventana

• Impact of antibiotic intake on the incidence of extended-spectrum β-lactamase–producing Enterobacterales in sub-Saharan Africa: results from a community-based longitudinal study se abre en una nueva pestaña/ventana

• Real-world clinical outcome of cefiderocol for treatment of multidrug-resistant non-fermenting, gram negative bacilli infections: a case series se abre en una nueva pestaña/ventana

• Macrolide therapy in Pseudomonas aeruginosa infections causes uL4 ribosomal protein mutations leading to high-level resistance se abre en una nueva pestaña/ventana

• The emergence of a multidrug resistant Salmonella Muenchen in Israel is associated with horizontal acquisition of the epidemic pESI plasmid se abre en una nueva pestaña/ventana

• Clinical consequences of very major errors with semi-automated testing systems for antimicrobial susceptibility of carbapenem-resistant Enterobacterales se abre en una nueva pestaña/ventana

• IDSA guidance and ESCMID guidelines: complementary approaches toward a care standard for MDR Gram-negative infections se abre en una nueva pestaña/ventana

• How I manage a patient with MRSA bacteraemia se abre en una nueva pestaña/ventana

• How to: screening for mcr-mediated resistance to colistin se abre en una nueva pestaña/ventana

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Current Opinion in Microbiology

• Nothing makes sense in drug resistance except in the light of evolution se abre en una nueva pestaña/ventana

• Interplay of emerging and established technologies drives innovation in natural product antibiotic discovery se abre en una nueva pestaña/ventana

• Present and future outlooks on environmental DNA-based methods for antibiotic discovery se abre en una nueva pestaña/ventana

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Epidemics

• Linking antimicrobial prescribing to antimicrobial resistance in the ICU: Before and after an antimicrobial stewardship program se abre en una nueva pestaña/ventana

• Transmission dynamics of an antimicrobial resistant Campylobacter jejuni lineage in New Zealand’s commercial poultry network se abre en una nueva pestaña/ventana

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Food Microbiology

• Determination and quantification of microbial communities and antimicrobial resistance on food through host DNA-depleted metagenomics se abre en una nueva pestaña/ventana

• A five-year study on prevalence and antimicrobial resistance of Campylobacter from poultry carcasses in Poland se abre en una nueva pestaña/ventana

• Combined metabolomics and transcriptomics analysis reveals the mechanism of antibiotic resistance of Salmonella enterica serovar Typhimurium after acidic stress se abre en una nueva pestaña/ventana

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Infection Prevention in Practice

• Management of BAME patients with a history of penicillin allergy: barriers to best practice and strategies to overcome these se abre en una nueva pestaña/ventana

• World Antimicrobial Resistance Awareness Week 2023: the overlooked challenges of antimicrobial stewardship se abre en una nueva pestaña/ventana

• Challenges of implementing antimicrobial stewardship tools in Low to Middle Income Countries (LMICs) se abre en una nueva pestaña/ventana

• Antimicrobial resistance as a super wicked problem: how do we engage the public to be part of the solution se abre en una nueva pestaña/ventana

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International Journal of Antimicrobial Agents

• Reducing the duration of antibiotic therapy in surgical patients through a specific nationwide antimicrobial stewardship program. A prospective, interventional cohort study se abre en una nueva pestaña/ventana

• Changes in the prevalence of pathogens causing hospital-acquired bacterial pneumonia and the impact of their antimicrobial resistance patterns on clinical outcomes: A propensity-score-matched study se abre en una nueva pestaña/ventana

• Effect of a national antibiotic stewardship intervention in China targeting carbapenem overuse: An interrupted time-series analysis se abre en una nueva pestaña/ventana

• Antimicrobial resistance surveillance: China's nearly 40-year effort se abre en una nueva pestaña/ventana

• The battle against fungi: lessons in antifungal stewardship from COVID 19 times se abre en una nueva pestaña/ventana

• Prescription of antibiotics by general practitioners for patients with a diagnosis of SARS- CoV-2 infection: Analysis of an electronic French health record se abre en una nueva pestaña/ventana

• Multidrug-resistant Gram-negative bacilli recovered from respiratory and blood specimens from adults: the ATLAS surveillance program in European hospitals, 2018–2020 se abre en una nueva pestaña/ventana

• Geographic patterns of carbapenem-resistant, multi-drug-resistant and difficult-to-treat Acinetobacter baumannii in the Asia-Pacific region: results from the Antimicrobial Testing Leadership and Surveillance (ATLAS) program, 2020 se abre en una nueva pestaña/ventana

• Long-term follow-up of HIV-1 multi-drug-resistant treatment-experienced participants treated with etravirine, raltegravir and boosted darunavir: towards drug-reduced regimen? ANRS CO3 Aquitaine Cohort 2007–2018 se abre en una nueva pestaña/ventana

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International Journal of Infectious Diseases

Editorial

• Antimicrobial resistance – a global problem in need of global solutions se abre en una nueva pestaña/ventana

Research articles

• Indications and classes of outpatient antibiotic prescriptions in Japan: A descriptive study using the national database of electronic health insurance claims, 2012–2015 se abre en una nueva pestaña/ventana

• Antibiotic use in Kenyan public hospitals: Prevalence, appropriateness and link to guideline availability se abre en una nueva pestaña/ventana

• Surgical site infections after pancreaticoduodenectomy: Preoperative biliary system interventions and antimicrobial prophylaxis se abre en una nueva pestaña/ventana

• Effectiveness of ceftazidime–avibactam versus colistin in treating carbapenem-resistant Enterobacteriaceae bacteremia se abre en una nueva pestaña/ventana

• Emergence of clinical isolates of highly carbapenem-resistant Klebsiella pneumoniae co-harboring blaNDM-5 and blaOXA-181 or -232 in Nepal se abre en una nueva pestaña/ventana

• In vitro efficacy of ceftazidime-avibactam, aztreonam-avibactam and other rescue antibiotics against carbapenem-resistant Enterobacterales from the Arabian Peninsula se abre en una nueva pestaña/ventana

• Value of routine whole genome sequencing for Mycobacterium tuberculosis drug resistance detection se abre en una nueva pestaña/ventana

• High prevalence of ESBL-producing Klebsiella pneumoniae in clinical samples from central Côte d'Ivoire se abre en una nueva pestaña/ventana

• Clonal expansion of colistin-resistant Acinetobacter baumannii isolates in Cape Town, South Africa se abre en una nueva pestaña/ventana

• Molecular epidemiology of Carbapenem-resistant Klebsiella pneumoniae in a paediatric hospital in China se abre en una nueva pestaña/ventana

Review

• Global Antimicrobial Stewardship with a Focus on Low- and Middle-Income Countries se abre en una nueva pestaña/ventana

• Impact of vaccines on antimicrobial resistance se abre en una nueva pestaña/ventana

• COVID-19 and antimicrobial stewardship: lessons learned, best practices, and future implications se abre en una nueva pestaña/ventana

• Global knowledge gaps on antimicrobial resistance in the human health sector: A scoping review se abre en una nueva pestaña/ventana

Perspectives

• Antibiotics and antimicrobial resistance in the COVID-19 era: Perspective from resource-limited settings se abre en una nueva pestaña/ventana

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iScience

• Synthetic antibacterial discovery of symbah-1, a macrocyclic β-hairpin peptide antibiotic se abre en una nueva pestaña/ventana

• A history of the MetaSUB consortium: Tracking urban microbes around the globe se abre en una nueva pestaña/ventana

• Metagenomic analysis reveals the dissemination mechanisms and risks of resistance genes in plateau lakes se abre en una nueva pestaña/ventana

• Bacterial memory in antibiotic resistance evolution and nanotechnology in evolutionary biology se abre en una nueva pestaña/ventana

• Characterization of a novel genus of jumbo phages and their application in wastewater treatment se abre en una nueva pestaña/ventana

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Journal of Global Antimicrobial Resistance

• Nosocomial Outbreak of Colistin-Resistant, Carbapenemase-Producing Klebsiella Pneumoniae ST11 in a Medical Intensive Care Unit se abre en una nueva pestaña/ventana

• Impact of antimicrobial stewardship 2018 on severe pneumonia with bacterial infection in PICU se abre en una nueva pestaña/ventana

• Emergence of optrA-mediated linezolid resistance in clinical isolates of Enterococcus faecalis from Argentina se abre en una nueva pestaña/ventana

• Comparison of ANN and LR models for predicting Carbapenem-resistant Klebsiella pneumoniae isolates from a southern province of China's RNSS data se abre en una nueva pestaña/ventana

• Prevalence of antibiotic resistance of Staphylococcus aureus in cystic fibrosis infection: A systematic review and meta-analysis se abre en una nueva pestaña/ventana

• Epidemiology of staphylococci species and their antimicrobial-resistance among patients with wound infection in Ethiopia: a systematic review and meta-analysis se abre en una nueva pestaña/ventana

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Journal of Hospital Infection

• Impact of Intensified Inpatient Clindamycin Stewardship Initiatives in Three Phases: A Pilot Quasi-Experimental Study se abre en una nueva pestaña/ventana

• The cost-effectiveness of a real-time spatiotemporal mapping surveillance system for meticillin-resistant Staphylococcus aureus prevention se abre en una nueva pestaña/ventana

• Virulence genes and plasmid replicon profiles of selected β-lactamase-producing Acinetobacter baumannii from orthopaedic patients and the environment in a tertiary referral hospital in Tanzania, East Africa se abre en una nueva pestaña/ventana

• Swimming pool policies for carriers of highly-resistant micro-organisms receiving rehabilitation care in the Netherlands se abre en una nueva pestaña/ventana

• Wastewater-based epidemiology for tracking bacterial diversity and antibiotic resistance in COVID-19 isolation hospitals in Qatar se abre en una nueva pestaña/ventana

• Qualitative analysis of healthcare provider perspectives to evaluating beta-lactam allergies se abre en una nueva pestaña/ventana

• Modelling hospital disinfectant against multi-drug-resistant dry surface biofilms grown under artificial human sweat se abre en una nueva pestaña/ventana

• Analysis of carbapenem-resistant strains isolated in a tertiary care hospital in Rawalpindi, Pakistan, during the years 2016 and 2020 se abre en una nueva pestaña/ventana

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Journal of Microbiological Methods

• Evaluation of metagenomic assembly methods for the detection and characterization of antimicrobial resistance determinants and associated mobilizable elements se abre en una nueva pestaña/ventana

• A rapid MALDI-TOF mass spectrometry-based method for categorization of Pseudomonas aeruginosa from blood cultures as susceptible or resistant to meropenem se abre en una nueva pestaña/ventana

• Comparison of FT-IR with whole-genome sequencing for identification of maternal-to‑neonate transmission of antibiotic-resistant bacteria se abre en una nueva pestaña/ventana

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Med

• Refractory Pseudomonas aeruginosa infections treated with phage PASA16: A compassionate use case series se abre en una nueva pestaña/ventana

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Microbes and Infection

• Nanomotion technology in combination with machine learning: a new approach for a rapid antibiotic susceptibility test for Mycobacterium tuberculosis se abre en una nueva pestaña/ventana

• Therapeutic potential of kaempferol on Streptococcus pneumoniae infection se abre en una nueva pestaña/ventana

• Crystal violet decolorization assay: a simplified colorimetric test for the rapid detection of multidrug-resistant Mycobacterium tuberculosis isolates se abre en una nueva pestaña/ventana

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Microbial Risk Analysis

• Estimating the likelihood of ESBL-producing E. coli carriage in slaughter-aged pigs following bacterial introduction onto a farm: A multiscale risk assessment se abre en una nueva pestaña/ventana

• Multidirectional dynamic model for the spread of extended-spectrum-B-lactamase-producing Escherichia coli in the Netherlands se abre en una nueva pestaña/ventana

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Microbiological Research

• The menace of colistin resistance across globe: Obstacles and opportunities in curbing its spread se abre en una nueva pestaña/ventana

• Genomic insight into the distribution and genetic environment of blaIMP-4 in clinical carbapenem-resistant Klebsiella pneumoniae strains in China se abre en una nueva pestaña/ventana

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Research in Microbiology

• Analysis of AcrB in Klebsiella pneumoniae reveals natural variants promoting enhanced multidrug resistance se abre en una nueva pestaña/ventana

• Vancomycin-resistant Enterococcus faecium and the emergence of new sequence types associated with hospital infection se abre en una nueva pestaña/ventana

• Bacteriophages potentiate the effect of antibiotics by eradication of persister cells and killing of biofilm-forming cells(opens in new tab/window) se abre en una nueva pestaña/ventana

• Transcription factor mce3R modulates antibiotics and disease persistence in Mycobacterium tuberculosis se abre en una nueva pestaña/ventana

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LabLinks: Antimicrobial resistance