BBA Collection Otto Warburg 2024: Protein structure formation and the role of chaperones This curated compilation, sourced from the family of ten BBA Journals over the period 2018-2024, serves as a tribute to Professor Dr. Johannes Buchner. Dr. Buchner is the 2024 recipient of the Otto Warburg Medal Award, an award which BBA is honoured to sponsor. Professor Buchner has made pioneering contributions to many different aspects of protein science, in particular to the role of chaperones in safeguarding protein folding and antibody stability. These proteins are โprotectorsโ, either of the organism itself or of the many different proteins whose correct folding is a prerequisite for their function. The articles compiled are original research and reviews published across the BBA journals that illustrate the breadth and complexity of these proteins.
Structural studies of the Hsp70/Hsp90 organizing protein of Plasmodium falciparum and its modulation of Hsp70 and Hsp90 ATPase activities ์ ํญ/์ฐฝ์์ ์ด๊ธฐ
Noeli S.M. Silva, Dayane E. Bertolino-Reis, Paulo R. Dores-Silva, Fรกtima B. Anneta, Thiago V. Seraphim, Leandro R.S. Barbosa, Jรบlio C. Borges, Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2020
Structural characterization of the N-terminal kinase-interacting domain of an Hsp90-cochaperone Cdc37 by CD and solution NMR spectroscopy ์ ํญ/์ฐฝ์์ ์ด๊ธฐ
Futoshi Ihama, Mami Yamamoto, Chojiro Kojima, Toshimichi Fujiwara, Katsumi Matsuzaki, Yoshihiko Miyata, Masaru Hoshino, Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2019
Detection of key sites of dimer dissociation and unfolding initiation during activation of acid-stress chaperone HdeA at low pH ์ ํญ/์ฐฝ์์ ์ด๊ธฐ
Marlyn A. Widjaja, Jafaeth S. Gomez, Jonathon M. Benson, Karin A. Crowhurst, Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2020
Biophysical characterization of human-cell-expressed, full-length ฮบI O18/O8, AL-09, ฮป6a, and Wil immunoglobulin light chains ์ ํญ/์ฐฝ์์ ์ด๊ธฐ
Pinaki Misra, Alexander Tischer, Lindsey Lampe, Valeria Pierluissi-Ruiz, Christopher J. Dick, Benoit Bragantini, Nikita Kormshchikov, Matthew Auton, Marina Ramirez-Alvarado, Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2024
Amyloid fibril formation by ฮฑS1- and ฮฒ-casein implies that fibril formation is a general property of casein proteins ์ ํญ/์ฐฝ์์ ์ด๊ธฐ
Elmira Bahraminejad, Devashi Paliwal, Margaret Sunde, Carl Holt, John A. Carver, David C. Thorn, Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2022
Engineering of conserved residues near antibody heavy chain complementary determining region 3 (HCDR3) improves both affinity and stability ์ ํญ/์ฐฝ์์ ์ด๊ธฐ
Merve Arslan, Tuฤรงe Uluรงay, Seyit Kale, Sibel Kalyoncu, Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2023
Structure and energetic basis of overrepresented ฮป light chain in systemic light chain amyloidosis patients ์ ํญ/์ฐฝ์์ ์ด๊ธฐ
Jun Zhao, Baohong Zhang, Jianwei Zhu, Ruth Nussinov, Buyong Ma, Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2018
Inhibition of amyloid fibril formation in the variable domain of ฮป6 light chain mutant Wil caused by the interaction between its unfolded state and epigallocatechin-3-O-gallate ์ ํญ/์ฐฝ์์ ์ด๊ธฐ
Yoshito Abe, Naoki Odawara, Nantanat Aeimhirunkailas, Hinako Shibata, Naoki Fujisaki, Hirofumi Tachibana, Tadashi Ueda, Biochimica et Biophysica Acta (BBA) - General Subjects, 2018
Localized conformational changes trigger the pH-induced fibrillogenesis of an amyloidogenic ฮป light chain protein ์ ํญ/์ฐฝ์์ ์ด๊ธฐ
Isabel Velรกzquez-Lรณpez, Gilberto Valdรฉs-Garcรญa, Sergio Romero Romero, Roberto Maya Martรญnez, Ana I. Leal-Cervantes, Miguel Costas, Rosana Sรกnchez-Lรณpez, Carlos Amero, Nina Pastor, D. Alejandro Fernรกndez Velasco, Biochimica et Biophysica Acta (BBA) - General Subjects, 2018
Chemical chaperone 4-phenylbutyric acid alleviates the aggregation of human familial pulmonary fibrosis-related mutant SP-A2 protein in part through effects on GRP78 ์ ํญ/์ฐฝ์์ ์ด๊ธฐ
Xu Jiang, Guodong Fang, Li Dong, Peifeng Jin, Lu Ding, Haizeng Zhang, Junming Fan, Sunzhong Mao, Xiaofang Fan, Yongsheng Gong, Yongyu Wang, Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2018
Protein quality control of DYRK family protein kinases by the Hsp90-Cdc37 molecular chaperone ์ ํญ/์ฐฝ์์ ์ด๊ธฐ
Yoshihiko Miyata, Eisuke Nishida, Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2021
Molecular chaperone function of stress inducible Hsp70 is critical for intracellular multiplication of Toxoplasma gondii ์ ํญ/์ฐฝ์์ ์ด๊ธฐ
Pallabi Mitra, Abhijit S. Deshmukh, Chinmayee Choudhury, Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2020
Amino acid transporter SLC6A14 depends on heat shock protein HSP90 in trafficking to the cell surface ์ ํญ/์ฐฝ์์ ์ด๊ธฐ
Karolina Rogala-Koziarska, ลukasz Samluk, Katarzyna A. Naลฤcz, Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2019
HSP90a promotes the resistance to oxaliplatin in HCC through regulating IDH1-induced cell competition ์ ํญ/์ฐฝ์์ ์ด๊ธฐ
Sikai Wang, Hongxia Cheng, Yilan Huang, Miaomiao Li, Dongmei Gao, Huaping Chen, Ruxiong Su, Kun Guo, Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2024
A novel role of HSP90 in regulating osteoclastogenesis by abrogating Rab11b-driven transport ์ ํญ/์ฐฝ์์ ์ด๊ธฐ
Manh Tien Tran, Yuka Okusha, Yunxia Feng, Chiharu Sogawa, Takanori Eguchi, Tomoko Kadowaki, Eiko Sakai, Takayuki Tsukuba, Kuniaki Okamoto, Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2021
Prospects and challenges of noncoding-RNA-mediated inhibition of heat shock protein 90 for cancer therapy ์ ํญ/์ฐฝ์์ ์ด๊ธฐ
Shria Mattoo, Abha Gupta, Manvee Chauhan, Akshi Agrawal, Subrata Kumar Pore,
Biochimica et Biophysica Acta (BBA) - Gene Regulatory Mechanisms, 2024
DNAJB12 and DNJB14 are non-redundant Hsp40 redox chaperones involved in endoplasmic reticulum protein reflux ์ ํญ/์ฐฝ์์ ์ด๊ธฐ
Aline Dias da Purificaรงรฃo, Victor Debbas, Leonardo Yuji Tanaka, Gabriele Verรดnica de Mello Gabriel, Joรฃo Wosniak Jรบnior, Tiphany Coralie De Bessa, Sheila Garcia-Rosa, Francisco Rafael Martins Laurindo, Percillia Victoria Santos Oliveira, Biochimica et Biophysica Acta (BBA) - General Subjects, 2023
Distinct dynamical features of plasmodial and human HSP70-HSP110 highlight the divergence in their chaperone-assisted protein folding ์ ํญ/์ฐฝ์์ ์ด๊ธฐ
Aradhya Tripathi, Sara Del Galdo, Balasubramanian Chandramouli, Niti Kumar, Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics, 2023
HSPA1A conformational mutants reveal a conserved structural unit in Hsp70 proteins ์ ํญ/์ฐฝ์์ ์ด๊ธฐ
Veronika Vandova, Pavla Vankova, Michal Durech, Josef Houser, Daniel Kavan, Petr Man, Petr Muller, Filip Trcka, Biochimica et Biophysica Acta (BBA) - General Subjects, 2020
Association of Hsp90 with p53 and Fizzy related homolog (Fzr) synchronizing Anaphase Promoting Complex (APC/C): An unexplored ally towards oncogenic pathway ์ ํญ/์ฐฝ์์ ์ด๊ธฐ
Sanghati Roy Chowdhury, Tirthankar Koley, Mandeep Singh, Abdul Samath Ethayathulla, Punit Kaur, Biochimica et Biophysica Acta (BBA) - Reviews on Cancer, 2023
Human HSPA9 (mtHsp70, mortalin) interacts with lipid bilayers containing cardiolipin, a major component of the inner mitochondrial membrane ์ ํญ/์ฐฝ์์ ์ด๊ธฐ
Paulo Roberto Dores-Silva, David M. Cauvi, Vanessa T.R. Kiraly, Jรบlio C. Borges, Antonio De Maio, Biochimica et Biophysica Acta (BBA) โ Biomembranes, 2020
Advances in chaperone-assisted RNA crystallography using synthetic antibodies ์ ํญ/์ฐฝ์์ ์ด๊ธฐ
Hasan Al Banna, Naba Krishna Das, Manju Ojha, Deepak Koirala, BBA Advances, 2023
The roles of the chaperone-like protein CpeZ and the phycoerythrobilin lyase CpeY in phycoerythrin biogenesis ์ ํญ/์ฐฝ์์ ์ด๊ธฐ
Christina M. Kronfel, Avijit Biswas, Jacob P. Frick, Andrian Gutu, Tyler Blensdorf, Jonathan A. Karty, David M. Kehoe, Wendy M. Schluchter, Biochimica et Biophysica Acta (BBA) โ Bioenergetics, 2019