American Association for Cancer Research® (AACR) Annual Meeting 2024

Article collection

We are proud to present a special collection of articles for the American Association for Cancer Research^® (AACR) Annual Meeting 2024. This curated selection showcases the cutting-edge advancements and novel perspectives published in journals from Elsevier's Oncology Journal Network. We invite you to explore this collection and delve deeper into the exciting advancements shaping the future of cancer research.

Annals of Oncology

• Circulating tumor DNA and radiological tumor volume identify patients at risk for relapse with resected, early-stage non-small-cell lung cancer abre em uma nova guia/janela

Blood Neoplasia

• Comparison of TP53 Mutations in Myelodysplasia and Acute Leukemia Suggests Divergent Roles in Initiation and Progression abre em uma nova guia/janela

Cancer Epidemiology

• Latin America and the Caribbean Code Against Cancer 1st Edition: A landmark for cancer prevention in the region abre em uma nova guia/janela

• Association of the affordable care act with perceived health care quality of cancer survivors abre em uma nova guia/janela

Cancer Letters

• Editorial: The progress and challenges of hematological malignancies in the era of big data and new therapy abre em uma nova guia/janela

• Immune-checkpoint inhibitor resistance in cancer treatment: Current progress and future directions abre em uma nova guia/janela

• The past, present, and future of liver cancer research in China abre em uma nova guia/janela

• Ferroptosis: Promising approach for cancer and cancer immunotherapy abre em uma nova guia/janela

• Tackling the current dilemma of immunotherapy in extensive-stage small cell lung cancer: A promising strategy of combining with radiotherapy abre em uma nova guia/janela

• Oncolytic adenovirus as pancreatic cancer-targeted therapy: Where do we go from here? abre em uma nova guia/janela

• Novel strategies optimize immunotherapy by improving the cytotoxic function of T cells for pancreatic cancer treatment abre em uma nova guia/janela

• PROTACs: Novel tools for improving immunotherapy in cancer abre em uma nova guia/janela

Cancer Pathogenesis and Therapy

• Role of T cells in cancer immunotherapy: Opportunities and challenges abre em uma nova guia/janela

• PI3K/AKT/mTOR pathway, hypoxia, and glucose metabolism: Potential targets to overcome radioresistance in small cell lung cancer abre em uma nova guia/janela

• Clinical characteristics and treatment outcomes of Chinese diffuse large B-cell lymphoma patients in the era of rituximab (2005–2018) abre em uma nova guia/janela

Cancer Treatment and Research Communications

• Antibody-drug conjugates, immune-checkpoint inhibitors, and their combination in advanced non-small cell lung cancer abre em uma nova guia/janela

Cancer Treatment Reviews

• Histology independent drug development – Is this the future for cancer drugs? abre em uma nova guia/janela

• Breaking barriers in triple negative breast cancer (TNBC) – Unleashing the power of antibody-drug conjugates (ADCs) abre em uma nova guia/janela

Chinese Medical Journal Pulmonary and Critical Care Medicine

• Role of c-Myc in lung cancer: Progress, challenges, and prospects abre em uma nova guia/janela

• Pyroptosis: A promising target for lung cancer therapy abre em uma nova guia/janela

• Changing profile of lung cancer clinical characteristics in China: Over 8-year population-based study abre em uma nova guia/janela

Clinical Breast Cancer

• Risk of Recurrence in Patients With HER2+ Early-Stage Breast Cancer: Literature Analysis of Patient and Disease Characteristics abre em uma nova guia/janela

• Efficacy and Safety of Trastuzumab Deruxtecan in Breast Cancer: A Systematic Review and Meta-Analysis abre em uma nova guia/janela

Clinical Colorectal Cancer

• Incidence of Disease Recurrence in Patients With Colon and Upper Rectum Adenocarcinoma Stage II and III Receiving Adjuvant Capecitabine Monotherapy: Do Number of Chemotherapy Cycles and Relative Dose Intensity of the Drug Play a Role? abre em uma nova guia/janela

• Systemic Therapy for Patients With Pancreatic Cancer: Current Approaches and Opportunities for Novel Avenues Toward Precision Medicine abre em uma nova guia/janela

Clinical Genitourinary Cancer

• The Impact of Blue Light Cystoscopy Use Among Nonmuscle Invasive Bladder Cancer Patients in an Equal Access Setting: Implications on Recurrence and Time to Recurrence abre em uma nova guia/janela

• A Phase I Study of Capivasertib in Combination With Abiraterone Acetate in Patients With Metastatic Castration-Resistant Prostate Cancer abre em uma nova guia/janela

Clinical Imaging

• A comprehensive survey of deep learning research on medical image analysis with focus on transfer learning abre em uma nova guia/janela

• Decoding radiology reports: Potential application of OpenAI ChatGPT to enhance patient understanding of diagnostic reports abre em uma nova guia/janela

• CT radiomics for differentiating oncocytoma from renal cell carcinomas: Systematic review and meta-analysis abre em uma nova guia/janela

Clinical Lung Cancer

• Amivantamab, an Epidermal Growth Factor Receptor (EGFR) and Mesenchymal-epithelial Transition Factor (MET) Bispecific Antibody, Designed to Enable Multiple Mechanisms of Action and Broad Clinical Applications abre em uma nova guia/janela

• A Multicenter Retrospective Chart Review of Clinical Outcomes Among Patients With KRAS G12C Mutant Non–Small Cell Lung Cancer abre em uma nova guia/janela

Clinical Lymphoma Myeloma and Leukemia

• Progression-Free Survival of Daratumumab Versus Bortezomib Triplet Combination With Lenalidomide and Dexamethasone in Transplant Ineligible Patients With Newly Diagnosed Multiple Myeloma: TAURUS Chart Review Study abre em uma nova guia/janela

• Recommendations for Management of Secondary Antibody Deficiency in Multiple Myeloma abre em uma nova guia/janela

Clinical Surgical Oncology

• Impact of diverting stoma on long-term survival in patients with rectal cancer: A nationwide study based on health insurance claims data abre em uma nova guia/janela

• Chinese guidelines for the diagnosis and comprehensive treatment of colorectal liver metastases (V. 2023) abre em uma nova guia/janela

Clinics

• Could be FOXO3a, miR-96-5p and miR-182-5p useful for Brazilian women with luminal A and triple negative breast cancers prognosis and target therapy? abre em uma nova guia/janela

• Programmed cell death-1 and its ligands: Current knowledge and possibilities in immunotherapy abre em uma nova guia/janela

Critical Reviews in Oncology/Hematology

• Characteristics of gastric cancer around the world abre em uma nova guia/janela

• Ferroptosis induction via targeting metabolic alterations in head and neck cancer abre em uma nova guia/janela

Current Problems in Cancer

• Folate Receptor as a Biomarker and Therapeutic Target in Solid Tumors abre em uma nova guia/janela

• Tisotumab vedotin in recurrent or metastatic cervical cancer abre em uma nova guia/janela

• Comparative effect of progressive relaxation technique and Benson's technique on anxiety and fatigue in cancer survivors - an experimental study abre em uma nova guia/janela

EJC: Paediatric Oncology

• The impact of infertility and physical late effects on psycho-social well-being of long-term childhood cancer survivors: A cross-sectional study abre em uma nova guia/janela

• Olfactory neuroblastoma in children and adolescents: The EXPeRT recommendations for diagnosis and management abre em uma nova guia/janela

EJC Skin Cancer

• Quality of life issues faced by patients with keratinocyte cancer: A systematic review abre em uma nova guia/janela

• Spontaneous haematoma: A unique immune-related adverse event alongside other cutaneous reactions in a patient treated with pembrolizumab for metastatic melanoma abre em uma nova guia/janela

• Merkel cell carcinoma with leptomeningeal involvement: A complex case report abre em uma nova guia/janela

ESMO Gastrointestinal Oncology

• Unleashing the power of anti-HER2 therapies in metastatic colorectal cancer: paving the way for a brighter future abre em uma nova guia/janela

ESMO Open

• Artificial intelligence for detection of microsatellite instability in colorectal cancer—a multicentric analysis of a pre-screening tool for clinical application abre em uma nova guia/janela

• Effectiveness of next-generation sequencing for patients with advanced non-small-cell lung cancer: a population-based registry study abre em uma nova guia/janela

ESMO Real World Data and Digital Oncology

• Relationship of tumor fraction in circulating tumor DNA with prognosis in patients with advanced urothelial cancer abre em uma nova guia/janela

European Journal of Cancer

• Recent advances and future strategies in first-line treatment of ES-SCLC abre em uma nova guia/janela

• Cross-trial comparisons for the adjuvant treatment of MSI colorectal cancer: dare to dream the future scenarios. abre em uma nova guia/janela

• Revolutionizing anti-HER2 therapies for extrahepatic cholangiocarcinoma and gallbladder cancer: Current advancements and future perspectives abre em uma nova guia/janela

• A new prognostic model in chemotherapy-treated patients with recurrent or metastatic head and neck cancer: An analysis of ECOG-ACRIN E1305 abre em uma nova guia/janela

Gynecologic Oncology

• Inclusion, diversity, equity, and access (IDEA) in gynecologic cancer clinical trials: A joint statement from GOG foundation and Society of Gynecologic Oncology (SGO) abre em uma nova guia/janela

• Enhanced recovery after surgery (ERAS®) society guidelines for gynecologic oncology: Addressing implementation challenges - 2023 update abre em uma nova guia/janela

• Financial toxicity: A practical review for gynecologic oncology teams to understand and address patient-level financial burdens abre em uma nova guia/janela

• Lunchbox trial: A randomized phase III trial of cisplatin and irradiation followed by carboplatin and paclitaxel versus sandwich therapy of carboplatin and paclitaxel followed by irradiation then carboplatin and paclitaxel for advanced endometrial carcinoma abre em uma nova guia/janela

Gynecologic Oncology Reports

• Strategies for prevention and management of ocular events occurring with mirvetuximab soravtansine abre em uma nova guia/janela

• Digital cervicography for cervical cancer screening in low-resource settings: A scoping review abre em uma nova guia/janela

• Activity of pembrolizumab and lenvatinib in mismatch repair deficient (dMMR) endometrial cancer patients who have failed pembrolizumab monotherapy: A case series abre em uma nova guia/janela

Hematology, Transfusion and Cell Therapy

• CAR-T cell therapy for multiple myeloma: a practical toolkit for treatment in Brazil abre em uma nova guia/janela

Immuno-Oncology and Technology

• CD47–SIRPα-targeted therapeutics: status and prospects abre em uma nova guia/janela

• Quantitative RNA assessment and long-term stability in the FFPE tumor samples using Digital Spatial Profiler abre em uma nova guia/janela

• Basics of advanced therapy medicinal product development in academic pharma and the role of a GMP simulation unit abre em uma nova guia/janela

Journal of Bone Oncology

• Management of bone metastasis and cancer treatment-induced bone loss during the COVID-19 pandemic: An international perspective and recommendations abre em uma nova guia/janela

• Optimization of a syngeneic murine model of bone metastasis abre em uma nova guia/janela

Journal of Cancer Policy

• Cross-cultural adaptation of the PROFFIT Instrument to measure financial toxicity in people living with cancer within a UK population abre em uma nova guia/janela

• Effect of a same day appointment initiative on racial disparities in access for radiation oncology abre em uma nova guia/janela

Journal of Geriatric Oncology

• Predicting future cancer incidence by age, race, ethnicity, and sex abre em uma nova guia/janela

• Impact of pharmaceutical care interventions on multidisciplinary care of older patients with cancer: A systematic review abre em uma nova guia/janela

• A scoping review of ageism towards older adults in cancer care abre em uma nova guia/janela

Journal of Liquid Biopsy

• Liquid biopsy in detecting early non-small cell lung cancer abre em uma nova guia/janela

• Real-time assessment of HER2 status in circulating tumor cells of breast cancer patients: Methods of detection and clinical implications abre em uma nova guia/janela

Journal of the National Cancer Center

• Cancer incidence and mortality in China, 2022 abre em uma nova guia/janela

• Chinese quality control indices for standardized diagnosis and treatment of renal cancer (2022 edition) abre em uma nova guia/janela

• The breast cancer tumor microenvironment and precision medicine: immunogenicity and conditions favoring response to immunotherapy abre em uma nova guia/janela

Leukemia Research

• From bone marrow failure syndromes to VEXAS: Disentangling clonal hematopoiesis, immune system, and molecular drivers abre em uma nova guia/janela

• Evaluation of the Simplified Score to Predict Early Relapse in Multiple Myeloma (S-ERMM) in the MMRF CoMMpass study abre em uma nova guia/janela

Leukemia Research Reports

• Real world experience with ropeginterferon alpha-2b (Besremi) in essential thrombocythaemia and polycythaemia vera following exposure to pegylated interferon alfa-2a (Pegasys) abre em uma nova guia/janela

• Allogeneic stem cell transplant for multiple myeloma & myelofibrosis with split-dose busulfan, fludarabine & cyclophosphamide abre em uma nova guia/janela

• Location, location, location: A mini-review of CEBPA variants in patients with acute myeloid leukemia abre em uma nova guia/janela

Lung Cancer

• Lurbinectedin in patients with small cell lung cancer with chemotherapy-free interval ≥30 days and without central nervous metastases abre em uma nova guia/janela

Medical Dosimetry

• Clinical target volume segmentation based on gross tumor volume using deep learning for head and neck cancer treatment abre em uma nova guia/janela

• Dosimetric benefits of 3D-printed modulated electron bolus following lumpectomy and whole-breast radiotherapy for left breast cancer abre em uma nova guia/janela

• Medical dosimetry virtual clinical education: Mentors’ perspectives abre em uma nova guia/janela

Neoplasia

• UALCAN: An update to the integrated cancer data analysis platform abre em uma nova guia/janela

• Recent progress and novel approaches to treating atypical teratoid rhabdoid tumor abre em uma nova guia/janela

• Acral melanoma: new insights into the immune and genomic landscape abre em uma nova guia/janela

• Pioneering models of pediatric brain tumors abre em uma nova guia/janela

• A sensitive and robust plasma-based DNA methylation panel for early detection of target gastrointestinal cancers abre em uma nova guia/janela

• Identification and characterization of circular RNAs as novel putative biomarkers to predict anti-PD-1 monotherapy response in metastatic melanoma patients – Knowledge from two independent international studies abre em uma nova guia/janela

• Primary central nervous system germ cell tumors in children and young adults: A review of controversies in diagnostic and treatment approach abre em uma nova guia/janela

• Dual inhibition of VEGF and PARP suppresses KRAS-mutant colorectal cancer abre em uma nova guia/janela

• Epigenome-wide DNA methylation profiling of portal vein tumor thrombosis (PVTT) tissues in hepatocellular carcinoma patients abre em uma nova guia/janela

• Current state of pediatric neuro-oncology imaging, challenges and future directions abre em uma nova guia/janela

• Indigenous peoples and inclusion in clinical and genomic research: Understanding the history and navigating contemporary engagement abre em uma nova guia/janela

Oral Oncology

• Pembrolizumab versus methotrexate, docetaxel, or cetuximab in recurrent or metastatic head and neck squamous cell carcinoma (KEYNOTE-040): Subgroup analysis by pattern of disease recurrence abre em uma nova guia/janela

• Functional considerations between flap and non-flap reconstruction in oral tongue cancer: A systematic review abre em uma nova guia/janela

• Immunochemotherapy alone or immunochemotherapy plus subsequent locoregional radiotherapy in de novo metastatic nasopharyngeal carcinoma abre em uma nova guia/janela

Oral Oncology Reports

• Bibliometrics study of the cancer research in the faculties of medicine and dentistry during Syrian crisis abre em uma nova guia/janela

• Immune-related adverse events following checkpoint inhibitor treatment in head and neck cancers: A comprehensive review abre em uma nova guia/janela

Photodiagnosis and Photodynamic Therapy

• Whole-course care in photodynamic therapy of colorectal cancer: A short communication abre em uma nova guia/janela

Radiation Medicine and Protection

• Mechanisms underlying FLASH radiotherapy, a novel way to enlarge the differential responses to ionizing radiation between normal and tumor tissues abre em uma nova guia/janela

• Prevention and treatment for radiation-induced skin injury during radiotherapy abre em uma nova guia/janela

• HIF-1 signaling: A key orchestrator of cancer radioresistance abre em uma nova guia/janela

Radiography

• Comparing the performance of full-field digital mammography and digital breast tomosynthesis in the post-treatment surveillance of patients with a history of breast cancer: A retrospective study abre em uma nova guia/janela

• Breast cancer patients’ experiences on their individual care pathway: A qualitative study abre em uma nova guia/janela

Surgical Oncology Insight

• Unsupervised clustering using multiple correspondence analysis reveals clinically-relevant demographic variables across multiple gastrointestinal cancers abre em uma nova guia/janela

• The prognostic role of post-operative cfDNA after resection of Colorectal Liver Metastases: A Systematic Review and Meta-Analysis abre em uma nova guia/janela

• The effect of the pandemic on colorectal cancer in the United States: An increased disease burden abre em uma nova guia/janela

The Breast

• Breast cancer highlights from 2023: Knowledge to guide practice and future research abre em uma nova guia/janela

• Best of the year: Advanced breast cancer in 2023 abre em uma nova guia/janela

Translational Oncology

• Epithelial-Mesenchymal Transition in Cancer: A Historical Overview abre em uma nova guia/janela

• 3D Bioprinted cancer models: Revolutionizing personalized cancer therapy abre em uma nova guia/janela

• MALAT-1: Immunomodulatory lncRNA hampering the innate and the adaptive immune arms in triple negative breast cancer abre em uma nova guia/janela

• Natural flavonoids exhibit potent anticancer activity by targeting microRNAs in cancer: A signature step hinting towards clinical perfection abre em uma nova guia/janela

• m6A demethylase FTO renders radioresistance of nasopharyngeal carcinoma via promoting OTUB1-mediated anti-ferroptosis abre em uma nova guia/janela

Elsevier’s Oncology Journal Network