Skip to main content

Unfortunately we don't fully support your browser. If you have the option to, please upgrade to a newer version or use Mozilla Firefox, Microsoft Edge, Google Chrome, or Safari 14 or newer. If you are unable to, and need support, please send us your feedback.

Elsevier
Publish with us
Cortex of Lymph Node
Lymphoid System

Cortex of Lymph Node

Cortex nodi lymphoidei

Read more

Quick Facts

The cortex is the outer portion of the node, consisting mainly of dense lymphoid tissue and follicles (Dorland, 2011).

Complete Anatomy
The world's most advanced 3D anatomy platform
Try it for Free

Structure/Morphology

The cortex is distinguishable by the presence of spherical lymphoid follicles, which are surrounded and separated by interfollicular (or diffuse) cortex.

Anatomical Relations

The cortex is located in the apical portion of the lymph node, between the subcapsular sinus and the paracortex. The lymphoid follicles present in the cortex are mainly populated with B cells and follicular dendritic cells (Standring, 2016). The number and the staining characteristics (during histological processing) of lymphoid follicles in the cortex greatly rely on the state of the antigen stimulation of the cells in the follicles.

Function

The cortex functions mainly to house quiescent lymphocytes, antigen-stimulated B-cells, and follicular dendritic cells.

References

Dorland, W. (2011) Dorland's Illustrated Medical Dictionary. 32nd edn. Philadelphia, USA: Elsevier Saunders.

Standring, S. (2016) Gray's Anatomy: The Anatomical Basis of Clinical Practice. Gray's Anatomy Series: Elsevier Limited.

Complete Anatomy

The world's most advanced 3D anatomy platform

Complete Anatomy