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Elsevier ClinicalKey Clinical Overview
Treatment
Initial medical resuscitation:
Resuscitate hemodynamically unstable patients with IV crystalloid solution and correct electrolyte abnormalities
Maintain patients on NPO status
Administer IV antiemetics (eg, ondansetron, metoclopramide) to reduce nausea, vomiting, and risk of aspiration
Decision for nasogastric tube placement depends on each patient; tube is not always required, but it is generally used in the following settings:
Significantly distended stomach or proximal small intestine
Persistent vomiting
Presence of irreducible hernia or volvulus
Complete obstruction
Generally used for decompression for a period of time followed by administration of enteral contrast material for water-soluble contrast challenge
Consult surgeon; promptly refer for findings suggestive of bowel ischemia or strangulation (eg, fever; leukocytosis; tachycardia; constant, noncrampy abdominal pain)
Bowel strangulation requires immediate surgery
Treat closed-loop small-bowel obstruction as a medical emergency because it can lead to vascular occlusion, mural ischemia, and death (in up to 35% of patients) if diagnosis is delayed
Urgent exploration is indicated for patients in whom contrast material fails to appear in the colon within 8 hours and who have mesenteric edema, small-bowel feces sign, and obstipation, or for patients with signs of strangulation
Provide antibiotic coverage for intra-abdominal infection if sepsis or perforation is suspected or if surgical exploration is planned
Include coverage against gram-negative and anaerobic organisms
Management may be nonoperative or operative:
Decision to manage relatively stable patients nonoperatively or surgically remains challenging
Delay in definitive treatment can result in need for urgent surgical intervention with increased morbidity and mortality compared with patients undergoing prompt intervention
Treatment
Decision to manage relatively stable patients nonoperatively or surgically remains challenging
Delay in definitive treatment can result in need for urgent surgical intervention with increased morbidity and mortality compared with patients undergoing prompt intervention
Patients with simple obstruction who undergo surgery are exposed to inherent surgical risks, longer hospitalizations, and adhesion-related complications (eg, recurrent obstruction)
Nonoperative treatment
Indications
Uncomplicated, partial small-bowel obstruction caused by adhesions in a patient with previous abdominopelvic surgery (high-grade or low-grade)
Obstruction as a result of Crohn disease or carcinomatosis
Obstruction in early postoperative period
Uncomplicated, recurrent small-bowel obstruction; make every attempt to avoid laparotomy in these patients
Includes administration of IV fluid and oral water-soluble contrast material (eg, diatrizoate meglumine, diatrizoate sodium) or water-soluble contrast challenge
Oral water-soluble contrast material or water-soluble contrast challenge
Consider hypertonic contrast material as adjuvant to conservative management in patients with partial small-bowel obstruction
Increases pressure gradient across obstruction site by causing fluid shift into intestinal lumen
Can aid in differentiating partial from complete obstruction before operative intervention
May shorten time to normal bowel function and decrease length of hospital stay, but it does not affect recurrence rate
Complications are rare but include anaphylactoid reaction and aspiration
Length of nonoperative management depends on obstruction cause and patient course
For patients at low risk for ischemia, continue nonoperative management until there is resolution, clinical deterioration, or failure to progress
Perform serial abdominal examinations every 4 to 8 hours
If nonoperative management is unsuccessful after 12 to 24 hours, initiate the water-soluble contrast challenge
Do not continue nonoperative management after 72 hours if obstruction is not resolving, even without clinical deterioration
Prolonged nonoperative treatment ( 10-14 days
Treatment
Do not continue nonoperative management after 72 hours if obstruction is not resolving, even without clinical deterioration
Prolonged nonoperative treatment ( 10-14 days
If patient has clinical deterioration or shows signs of peritonitis, emergency surgery is indicated (as opposed to further radiologic studies that delay treatment)
Operative treatment (laparoscopic adhesiolysis or laparotomy)
Indications
Complete bowel obstruction (generally first line treatment)
Partial obstruction that is not improving with nonoperative management
Signs of ischemia, peritonitis, or bowel strangulation on admission or at any time during nonoperative management
Obstruction caused by irreducible hernia or volvulus
Timing of surgery based on obstruction cause and presence of complications
Emergent surgery is indicated for patients with signs of small-bowel obstruction complicated by ischemia, peritonitis, or strangulation
If surgery is required for patients with postoperative adhesive bowel obstruction, plan surgery for sooner than 10 to 14 days after the previous surgery; after this time, adhesions are the most tenacious, poorly defined, and vascular, increasing risk for iatrogenic bowel injury and fistula formation
After 10 to 14 days, patients with uncomplicated disease (no signs of peritonitis, perforation, ischemia, or strangulation) may be safer to continue nonoperative management for 6 to 8 weeks with use of nasogastric decompression and total parenteral nutrition
After surgical release of obstruction, determine severity of ischemia to inform the need for bowel resection
Bowel resection is indicated for necrotic, strangulated, or gangrenous bowel (identified by dark blue to black coloring and possibly a foul odor) to prevent sepsis
Treatment
Bowel resection is indicated for necrotic, strangulated, or gangrenous bowel (identified by dark blue to black coloring and possibly a foul odor) to prevent sepsis
Resection may not be required for less-severe ischemia, as indicated by a return to normal color after release of obstruction, palpable arterial pulsations, audible Doppler signals on the antimesenteric border, and peristalsis
Treatment considerations by obstruction cause:
Malignant neoplasm
For patients with incurable neoplastic small-bowel obstruction, treatment focus is on maximizing palliation and minimizing complications and hospital stay
Provide symptom relief with analgesic, antiemetic, and antisecretory agents in conjunction with other treatment options
Surgical treatments include primary resection and reconstruction, internal bypass, or palliative diversion
Endoscopic and interventional techniques
Decompressive gastrostomy tubes may provide some relief of intractable nausea and vomiting
Self-expanding metal stents, passed endoscopically or fluoroscopically, may allow increase in lumen size in a subset of patients
Percutaneous endoscopic gastrostomy may be considered if laparotomy is contraindicated
In some cases, no available interventions can be performed without significant risk of harm to the patient
Hernia
Immediate surgery indicated for irreducible or strangulated hernia
Resolution of obstruction after manual hernia reduction requires hospital admission for observation and repair before discharge to prevent recurrence
Early postoperative adhesions
Initial management consists of tube decompression and parenteral nutrition
Consider surgical care for patients with postoperative adhesive bowel obstruction if within 10- to 14-day period after primary surgery
Adhesions after this time are the most tenacious, poorly defined, and vascular, increasing risk for iatrogenic bowel injury and fistula formation
Treatment
Adhesions after this time are the most tenacious, poorly defined, and vascular, increasing risk for iatrogenic bowel injury and fistula formation
For patients for whom this time frame has elapsed, consider long-term tube decompression and parenteral nutrition
If signs of strangulation or ischemia are present, surgical exploration is indicated
Crohn disease
In the acute phase, patients can be managed nonoperatively with hydration, nasogastric decompression, and parenteral nutrition
For patients with a history of Crohn disease, allow 7 to 10 days of nonoperative treatment before considering surgery
Anti-inflammatory medication is indicated for those patients with disease unresponsive to nonoperative treatment
Radiation enteropathy
In acute setting, generally treated nonoperatively with tube decompression and possibly corticosteroids
In chronic cases, laparotomy is typically required, with possible resection of irradiated bowel or bypass of affected area