American Association for Cancer Research® (AACR) Annual Meeting 2024

Article collection

We are proud to present a special collection of articles for the American Association for Cancer Research^® (AACR) Annual Meeting 2024. This curated selection showcases the cutting-edge advancements and novel perspectives published in journals from Elsevier's Oncology Journal Network. We invite you to explore this collection and delve deeper into the exciting advancements shaping the future of cancer research.

Annals of Oncology

• Circulating tumor DNA and radiological tumor volume identify patients at risk for relapse with resected, early-stage non-small-cell lung cancer Wird in neuem Tab/Fenster geöffnet

Blood Neoplasia

• Comparison of TP53 Mutations in Myelodysplasia and Acute Leukemia Suggests Divergent Roles in Initiation and Progression Wird in neuem Tab/Fenster geöffnet

Cancer Epidemiology

• Latin America and the Caribbean Code Against Cancer 1st Edition: A landmark for cancer prevention in the region Wird in neuem Tab/Fenster geöffnet

• Association of the affordable care act with perceived health care quality of cancer survivors Wird in neuem Tab/Fenster geöffnet

Cancer Letters

• Editorial: The progress and challenges of hematological malignancies in the era of big data and new therapy Wird in neuem Tab/Fenster geöffnet

• Immune-checkpoint inhibitor resistance in cancer treatment: Current progress and future directions Wird in neuem Tab/Fenster geöffnet

• The past, present, and future of liver cancer research in China Wird in neuem Tab/Fenster geöffnet

• Ferroptosis: Promising approach for cancer and cancer immunotherapy Wird in neuem Tab/Fenster geöffnet

• Tackling the current dilemma of immunotherapy in extensive-stage small cell lung cancer: A promising strategy of combining with radiotherapy Wird in neuem Tab/Fenster geöffnet

• Oncolytic adenovirus as pancreatic cancer-targeted therapy: Where do we go from here? Wird in neuem Tab/Fenster geöffnet

• Novel strategies optimize immunotherapy by improving the cytotoxic function of T cells for pancreatic cancer treatment Wird in neuem Tab/Fenster geöffnet

• PROTACs: Novel tools for improving immunotherapy in cancer Wird in neuem Tab/Fenster geöffnet

Cancer Pathogenesis and Therapy

• Role of T cells in cancer immunotherapy: Opportunities and challenges Wird in neuem Tab/Fenster geöffnet

• PI3K/AKT/mTOR pathway, hypoxia, and glucose metabolism: Potential targets to overcome radioresistance in small cell lung cancer Wird in neuem Tab/Fenster geöffnet

• Clinical characteristics and treatment outcomes of Chinese diffuse large B-cell lymphoma patients in the era of rituximab (2005–2018) Wird in neuem Tab/Fenster geöffnet

Cancer Treatment and Research Communications

• Antibody-drug conjugates, immune-checkpoint inhibitors, and their combination in advanced non-small cell lung cancer Wird in neuem Tab/Fenster geöffnet

Cancer Treatment Reviews

• Histology independent drug development – Is this the future for cancer drugs? Wird in neuem Tab/Fenster geöffnet

• Breaking barriers in triple negative breast cancer (TNBC) – Unleashing the power of antibody-drug conjugates (ADCs) Wird in neuem Tab/Fenster geöffnet

Chinese Medical Journal Pulmonary and Critical Care Medicine

• Role of c-Myc in lung cancer: Progress, challenges, and prospects Wird in neuem Tab/Fenster geöffnet

• Pyroptosis: A promising target for lung cancer therapy Wird in neuem Tab/Fenster geöffnet

• Changing profile of lung cancer clinical characteristics in China: Over 8-year population-based study Wird in neuem Tab/Fenster geöffnet

Clinical Breast Cancer

• Risk of Recurrence in Patients With HER2+ Early-Stage Breast Cancer: Literature Analysis of Patient and Disease Characteristics Wird in neuem Tab/Fenster geöffnet

• Efficacy and Safety of Trastuzumab Deruxtecan in Breast Cancer: A Systematic Review and Meta-Analysis Wird in neuem Tab/Fenster geöffnet

Clinical Colorectal Cancer

• Incidence of Disease Recurrence in Patients With Colon and Upper Rectum Adenocarcinoma Stage II and III Receiving Adjuvant Capecitabine Monotherapy: Do Number of Chemotherapy Cycles and Relative Dose Intensity of the Drug Play a Role? Wird in neuem Tab/Fenster geöffnet

• Systemic Therapy for Patients With Pancreatic Cancer: Current Approaches and Opportunities for Novel Avenues Toward Precision Medicine Wird in neuem Tab/Fenster geöffnet

Clinical Genitourinary Cancer

• The Impact of Blue Light Cystoscopy Use Among Nonmuscle Invasive Bladder Cancer Patients in an Equal Access Setting: Implications on Recurrence and Time to Recurrence Wird in neuem Tab/Fenster geöffnet

• A Phase I Study of Capivasertib in Combination With Abiraterone Acetate in Patients With Metastatic Castration-Resistant Prostate Cancer Wird in neuem Tab/Fenster geöffnet

Clinical Imaging

• A comprehensive survey of deep learning research on medical image analysis with focus on transfer learning Wird in neuem Tab/Fenster geöffnet

• Decoding radiology reports: Potential application of OpenAI ChatGPT to enhance patient understanding of diagnostic reports Wird in neuem Tab/Fenster geöffnet

• CT radiomics for differentiating oncocytoma from renal cell carcinomas: Systematic review and meta-analysis Wird in neuem Tab/Fenster geöffnet

Clinical Lung Cancer

• Amivantamab, an Epidermal Growth Factor Receptor (EGFR) and Mesenchymal-epithelial Transition Factor (MET) Bispecific Antibody, Designed to Enable Multiple Mechanisms of Action and Broad Clinical Applications Wird in neuem Tab/Fenster geöffnet

• A Multicenter Retrospective Chart Review of Clinical Outcomes Among Patients With KRAS G12C Mutant Non–Small Cell Lung Cancer Wird in neuem Tab/Fenster geöffnet

Clinical Lymphoma Myeloma and Leukemia

• Progression-Free Survival of Daratumumab Versus Bortezomib Triplet Combination With Lenalidomide and Dexamethasone in Transplant Ineligible Patients With Newly Diagnosed Multiple Myeloma: TAURUS Chart Review Study Wird in neuem Tab/Fenster geöffnet

• Recommendations for Management of Secondary Antibody Deficiency in Multiple Myeloma Wird in neuem Tab/Fenster geöffnet

Clinical Surgical Oncology

• Impact of diverting stoma on long-term survival in patients with rectal cancer: A nationwide study based on health insurance claims data Wird in neuem Tab/Fenster geöffnet

• Chinese guidelines for the diagnosis and comprehensive treatment of colorectal liver metastases (V. 2023) Wird in neuem Tab/Fenster geöffnet

Clinics

• Could be FOXO3a, miR-96-5p and miR-182-5p useful for Brazilian women with luminal A and triple negative breast cancers prognosis and target therapy? Wird in neuem Tab/Fenster geöffnet

• Programmed cell death-1 and its ligands: Current knowledge and possibilities in immunotherapy Wird in neuem Tab/Fenster geöffnet

Critical Reviews in Oncology/Hematology

• Characteristics of gastric cancer around the world Wird in neuem Tab/Fenster geöffnet

• Ferroptosis induction via targeting metabolic alterations in head and neck cancer Wird in neuem Tab/Fenster geöffnet

Current Problems in Cancer

• Folate Receptor as a Biomarker and Therapeutic Target in Solid Tumors Wird in neuem Tab/Fenster geöffnet

• Tisotumab vedotin in recurrent or metastatic cervical cancer Wird in neuem Tab/Fenster geöffnet

• Comparative effect of progressive relaxation technique and Benson's technique on anxiety and fatigue in cancer survivors - an experimental study Wird in neuem Tab/Fenster geöffnet

EJC: Paediatric Oncology

• The impact of infertility and physical late effects on psycho-social well-being of long-term childhood cancer survivors: A cross-sectional study Wird in neuem Tab/Fenster geöffnet

• Olfactory neuroblastoma in children and adolescents: The EXPeRT recommendations for diagnosis and management Wird in neuem Tab/Fenster geöffnet

EJC Skin Cancer

• Quality of life issues faced by patients with keratinocyte cancer: A systematic review Wird in neuem Tab/Fenster geöffnet

• Spontaneous haematoma: A unique immune-related adverse event alongside other cutaneous reactions in a patient treated with pembrolizumab for metastatic melanoma Wird in neuem Tab/Fenster geöffnet

• Merkel cell carcinoma with leptomeningeal involvement: A complex case report Wird in neuem Tab/Fenster geöffnet

ESMO Gastrointestinal Oncology

• Unleashing the power of anti-HER2 therapies in metastatic colorectal cancer: paving the way for a brighter future Wird in neuem Tab/Fenster geöffnet

ESMO Open

• Artificial intelligence for detection of microsatellite instability in colorectal cancer—a multicentric analysis of a pre-screening tool for clinical application Wird in neuem Tab/Fenster geöffnet

• Effectiveness of next-generation sequencing for patients with advanced non-small-cell lung cancer: a population-based registry study Wird in neuem Tab/Fenster geöffnet

ESMO Real World Data and Digital Oncology

• Relationship of tumor fraction in circulating tumor DNA with prognosis in patients with advanced urothelial cancer Wird in neuem Tab/Fenster geöffnet

European Journal of Cancer

• Recent advances and future strategies in first-line treatment of ES-SCLC Wird in neuem Tab/Fenster geöffnet

• Cross-trial comparisons for the adjuvant treatment of MSI colorectal cancer: dare to dream the future scenarios. Wird in neuem Tab/Fenster geöffnet

• Revolutionizing anti-HER2 therapies for extrahepatic cholangiocarcinoma and gallbladder cancer: Current advancements and future perspectives Wird in neuem Tab/Fenster geöffnet

• A new prognostic model in chemotherapy-treated patients with recurrent or metastatic head and neck cancer: An analysis of ECOG-ACRIN E1305 Wird in neuem Tab/Fenster geöffnet

Gynecologic Oncology

• Inclusion, diversity, equity, and access (IDEA) in gynecologic cancer clinical trials: A joint statement from GOG foundation and Society of Gynecologic Oncology (SGO) Wird in neuem Tab/Fenster geöffnet

• Enhanced recovery after surgery (ERAS®) society guidelines for gynecologic oncology: Addressing implementation challenges - 2023 update Wird in neuem Tab/Fenster geöffnet

• Financial toxicity: A practical review for gynecologic oncology teams to understand and address patient-level financial burdens Wird in neuem Tab/Fenster geöffnet

• Lunchbox trial: A randomized phase III trial of cisplatin and irradiation followed by carboplatin and paclitaxel versus sandwich therapy of carboplatin and paclitaxel followed by irradiation then carboplatin and paclitaxel for advanced endometrial carcinoma Wird in neuem Tab/Fenster geöffnet

Gynecologic Oncology Reports

• Strategies for prevention and management of ocular events occurring with mirvetuximab soravtansine Wird in neuem Tab/Fenster geöffnet

• Digital cervicography for cervical cancer screening in low-resource settings: A scoping review Wird in neuem Tab/Fenster geöffnet

• Activity of pembrolizumab and lenvatinib in mismatch repair deficient (dMMR) endometrial cancer patients who have failed pembrolizumab monotherapy: A case series Wird in neuem Tab/Fenster geöffnet

Hematology, Transfusion and Cell Therapy

• CAR-T cell therapy for multiple myeloma: a practical toolkit for treatment in Brazil Wird in neuem Tab/Fenster geöffnet

Immuno-Oncology and Technology

• CD47–SIRPα-targeted therapeutics: status and prospects Wird in neuem Tab/Fenster geöffnet

• Quantitative RNA assessment and long-term stability in the FFPE tumor samples using Digital Spatial Profiler Wird in neuem Tab/Fenster geöffnet

• Basics of advanced therapy medicinal product development in academic pharma and the role of a GMP simulation unit Wird in neuem Tab/Fenster geöffnet

Journal of Bone Oncology

• Management of bone metastasis and cancer treatment-induced bone loss during the COVID-19 pandemic: An international perspective and recommendations Wird in neuem Tab/Fenster geöffnet

• Optimization of a syngeneic murine model of bone metastasis Wird in neuem Tab/Fenster geöffnet

Journal of Cancer Policy

• Cross-cultural adaptation of the PROFFIT Instrument to measure financial toxicity in people living with cancer within a UK population Wird in neuem Tab/Fenster geöffnet

• Effect of a same day appointment initiative on racial disparities in access for radiation oncology Wird in neuem Tab/Fenster geöffnet

Journal of Geriatric Oncology

• Predicting future cancer incidence by age, race, ethnicity, and sex Wird in neuem Tab/Fenster geöffnet

• Impact of pharmaceutical care interventions on multidisciplinary care of older patients with cancer: A systematic review Wird in neuem Tab/Fenster geöffnet

• A scoping review of ageism towards older adults in cancer care Wird in neuem Tab/Fenster geöffnet

Journal of Liquid Biopsy

• Liquid biopsy in detecting early non-small cell lung cancer Wird in neuem Tab/Fenster geöffnet

• Real-time assessment of HER2 status in circulating tumor cells of breast cancer patients: Methods of detection and clinical implications Wird in neuem Tab/Fenster geöffnet

Journal of the National Cancer Center

• Cancer incidence and mortality in China, 2022 Wird in neuem Tab/Fenster geöffnet

• Chinese quality control indices for standardized diagnosis and treatment of renal cancer (2022 edition) Wird in neuem Tab/Fenster geöffnet

• The breast cancer tumor microenvironment and precision medicine: immunogenicity and conditions favoring response to immunotherapy Wird in neuem Tab/Fenster geöffnet

Leukemia Research

• From bone marrow failure syndromes to VEXAS: Disentangling clonal hematopoiesis, immune system, and molecular drivers Wird in neuem Tab/Fenster geöffnet

• Evaluation of the Simplified Score to Predict Early Relapse in Multiple Myeloma (S-ERMM) in the MMRF CoMMpass study Wird in neuem Tab/Fenster geöffnet

Leukemia Research Reports

• Real world experience with ropeginterferon alpha-2b (Besremi) in essential thrombocythaemia and polycythaemia vera following exposure to pegylated interferon alfa-2a (Pegasys) Wird in neuem Tab/Fenster geöffnet

• Allogeneic stem cell transplant for multiple myeloma & myelofibrosis with split-dose busulfan, fludarabine & cyclophosphamide Wird in neuem Tab/Fenster geöffnet

• Location, location, location: A mini-review of CEBPA variants in patients with acute myeloid leukemia Wird in neuem Tab/Fenster geöffnet

Lung Cancer

• Lurbinectedin in patients with small cell lung cancer with chemotherapy-free interval ≥30 days and without central nervous metastases Wird in neuem Tab/Fenster geöffnet

Medical Dosimetry

• Clinical target volume segmentation based on gross tumor volume using deep learning for head and neck cancer treatment Wird in neuem Tab/Fenster geöffnet

• Dosimetric benefits of 3D-printed modulated electron bolus following lumpectomy and whole-breast radiotherapy for left breast cancer Wird in neuem Tab/Fenster geöffnet

• Medical dosimetry virtual clinical education: Mentors’ perspectives Wird in neuem Tab/Fenster geöffnet

Neoplasia

• UALCAN: An update to the integrated cancer data analysis platform Wird in neuem Tab/Fenster geöffnet

• Recent progress and novel approaches to treating atypical teratoid rhabdoid tumor Wird in neuem Tab/Fenster geöffnet

• Acral melanoma: new insights into the immune and genomic landscape Wird in neuem Tab/Fenster geöffnet

• Pioneering models of pediatric brain tumors Wird in neuem Tab/Fenster geöffnet

• A sensitive and robust plasma-based DNA methylation panel for early detection of target gastrointestinal cancers Wird in neuem Tab/Fenster geöffnet

• Identification and characterization of circular RNAs as novel putative biomarkers to predict anti-PD-1 monotherapy response in metastatic melanoma patients – Knowledge from two independent international studies Wird in neuem Tab/Fenster geöffnet

• Primary central nervous system germ cell tumors in children and young adults: A review of controversies in diagnostic and treatment approach Wird in neuem Tab/Fenster geöffnet

• Dual inhibition of VEGF and PARP suppresses KRAS-mutant colorectal cancer Wird in neuem Tab/Fenster geöffnet

• Epigenome-wide DNA methylation profiling of portal vein tumor thrombosis (PVTT) tissues in hepatocellular carcinoma patients Wird in neuem Tab/Fenster geöffnet

• Current state of pediatric neuro-oncology imaging, challenges and future directions Wird in neuem Tab/Fenster geöffnet

• Indigenous peoples and inclusion in clinical and genomic research: Understanding the history and navigating contemporary engagement Wird in neuem Tab/Fenster geöffnet

Oral Oncology

• Pembrolizumab versus methotrexate, docetaxel, or cetuximab in recurrent or metastatic head and neck squamous cell carcinoma (KEYNOTE-040): Subgroup analysis by pattern of disease recurrence Wird in neuem Tab/Fenster geöffnet

• Functional considerations between flap and non-flap reconstruction in oral tongue cancer: A systematic review Wird in neuem Tab/Fenster geöffnet

• Immunochemotherapy alone or immunochemotherapy plus subsequent locoregional radiotherapy in de novo metastatic nasopharyngeal carcinoma Wird in neuem Tab/Fenster geöffnet

Oral Oncology Reports

• Bibliometrics study of the cancer research in the faculties of medicine and dentistry during Syrian crisis Wird in neuem Tab/Fenster geöffnet

• Immune-related adverse events following checkpoint inhibitor treatment in head and neck cancers: A comprehensive review Wird in neuem Tab/Fenster geöffnet

Photodiagnosis and Photodynamic Therapy

• Whole-course care in photodynamic therapy of colorectal cancer: A short communication Wird in neuem Tab/Fenster geöffnet

Radiation Medicine and Protection

• Mechanisms underlying FLASH radiotherapy, a novel way to enlarge the differential responses to ionizing radiation between normal and tumor tissues Wird in neuem Tab/Fenster geöffnet

• Prevention and treatment for radiation-induced skin injury during radiotherapy Wird in neuem Tab/Fenster geöffnet

• HIF-1 signaling: A key orchestrator of cancer radioresistance Wird in neuem Tab/Fenster geöffnet

Radiography

• Comparing the performance of full-field digital mammography and digital breast tomosynthesis in the post-treatment surveillance of patients with a history of breast cancer: A retrospective study Wird in neuem Tab/Fenster geöffnet

• Breast cancer patients’ experiences on their individual care pathway: A qualitative study Wird in neuem Tab/Fenster geöffnet

Surgical Oncology Insight

• Unsupervised clustering using multiple correspondence analysis reveals clinically-relevant demographic variables across multiple gastrointestinal cancers Wird in neuem Tab/Fenster geöffnet

• The prognostic role of post-operative cfDNA after resection of Colorectal Liver Metastases: A Systematic Review and Meta-Analysis Wird in neuem Tab/Fenster geöffnet

• The effect of the pandemic on colorectal cancer in the United States: An increased disease burden Wird in neuem Tab/Fenster geöffnet

The Breast

• Breast cancer highlights from 2023: Knowledge to guide practice and future research Wird in neuem Tab/Fenster geöffnet

• Best of the year: Advanced breast cancer in 2023 Wird in neuem Tab/Fenster geöffnet

Translational Oncology

• Epithelial-Mesenchymal Transition in Cancer: A Historical Overview Wird in neuem Tab/Fenster geöffnet

• 3D Bioprinted cancer models: Revolutionizing personalized cancer therapy Wird in neuem Tab/Fenster geöffnet

• MALAT-1: Immunomodulatory lncRNA hampering the innate and the adaptive immune arms in triple negative breast cancer Wird in neuem Tab/Fenster geöffnet

• Natural flavonoids exhibit potent anticancer activity by targeting microRNAs in cancer: A signature step hinting towards clinical perfection Wird in neuem Tab/Fenster geöffnet

• m6A demethylase FTO renders radioresistance of nasopharyngeal carcinoma via promoting OTUB1-mediated anti-ferroptosis Wird in neuem Tab/Fenster geöffnet

Elsevier’s Oncology Journal Network