Simplify regulatory searches with PharmaPendium AI
PharmaPendium 支援藥物安全性和有效性決策，以獲得更好的藥物結果
您需要高質量的數據來充滿信心地發現、創新和開發。PharmaPendium 將無與倫比的監管和藥物數據與全文搜索和預測工具相結合。使用 PharmaPendium 減少動物試驗並更快地推出藥物。
被 FDA 和世界頂級製藥公司使用
Get critical insights to predict the success or failure of drug candidates as early as possible
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To advance the best drug candidates, you want to prove better performance. PharmaPendium has user-friendly tools to help you analyze safety, deliverability and efficacy data.
Predict drug-drug interactions with confidence
Predict the risk of off-target adverse drug reactions (safety margin)
Access data with a translational view across preclinical, clinical and post-market, including:
Preclinical and clinical safety
Animal models
Adverse events (MedDRA)
Pharmacokinetic parameters
Metabolism and transport
Clinical trial and endpoints
Post-market reports (FAERS)
Make informed decisions to increase the success of regulatory submissions
Minimize regulatory cycling and avoid failing approval with PharmaPendium.
Discover complete regulatory packages from the EMA and FDA, and FDA Advisory Committee Meeting Documents
Explore previous regulatory submissions and learn from precedents to predict agencies’ requirements
Benchmark against approved and withdrawn drugs with the same mechanism of action as your drug candidates
Rapidly respond to regulatory questions using comparative data from FDA/EMA drug approval and review documents
分析候選藥物的毒性，並使用新的 Tox Navigator 推進 3R
Tox Navigator 是與輝瑞公司合作開發的，包括來自監管文件和科學文章的毒性數據。
Tox Navigator 支援 3R 和患者安全評估，可説明您：
將動物劑量轉換為人類當量劑量
利用現有數據減少動物研究數量並設計更高效的研究
調查不同物種的藥物不良反應
集成計算機模型和其他非動物試驗方法
通過關注具有良好安全性的候選者來優化研究工作
互聯、可配置的解決方案，用於研發創新
利用愛思唯爾的 PharmaPendium 和 藥物研發解決方案組合推進您的研究。
充滿信心地進行創新，並得到以下支援：
從監管數據到同行評審的科學文獻的可信質量資訊
為數據轉換以及分析和預測工具提供支援的創新技術
領域和數據科學專業知識，通過數據解決方案解決研發複雜問題
資訊完整性對您的進步至關重要。發現提供關鍵見解的可信數據和工具。
讓我們共同塑造進步。
Find precise data to advance your drug portfolio
FDA 和 EMA 檔
FDA 和 EMA 檔
利用 PharmaPendium 的強大功能，提供完整的 FDA 和 EMA 批准包以及重要的 FDA 諮詢委員會會議檔，這是其他工具所無法比擬的。
Enhanced visualization
Enhanced visualization
Seamlessly move from table view to interactive charts, graphs and visual aids to easily interrogate and interpret data.
Predictive tools
Predictive tools
Predict harmful DDIs using the DDI Risk Calculator and the risk of off-target adverse events using the Safety Margin Tool.
無與倫比的搜索功能
無與倫比的搜索功能
使用標準化數據按不良事件 （MedDRA）、靶點、適應症、藥物和終點查找資訊。結果頁面彌合了臨床前和臨床的鴻溝。
來自FAERS的真實世界證據
來自FAERS的真實世界證據
在FAERS（FDA不良事件報告系統）中搜索超過1900萬份報告，從真實世界證據和上市後藥物安全性中查找任何不良事件。
高品質數據集
高品質數據集
PharmaPendium 的高品質數據集可供平臺外使用。將數據嵌入到您的工作流程和模型中，以實現更準確的搜索和預測。
"... PharmaPendium excels in retrieving specific toxicity observations across approval documents categorized by drug and species."
GB
Guy Bouvier, PhD, ERT
Groupe Pierre Fabre 的 Director, Toxicology & Product Safety
Frequently asked questions
PharmaPendium Support CenterContinuous development and improvement of PharmaPendium has been achieved in collaboration with the FDA for 17 years, as well as with leading pharma partners like Novartis, Sanofi, Merck, Servier and Boehringer Ingelheim.
PharmaPendium is used by:
Toxicologists and safety pharmacologists
DMPK specialists
Clinical researchers
Regulatory affairs experts
Global patient safety experts
Data scientists
PharmaPendium provides you with unique content, all in one place. PharmaPendium data sources include:
Full FDA approval packages
Full EMA approval documents
FDA Advisory Committee Documents
FDA Adverse Event Reporting System (FAERS)
FDA classic collection (covering 1938-1991)
DESI (Drug Efficacy Study Implementation) documents
Meyler's 16th Edition
Mosby's Drug Consult™️
Scientific articles
We extract, organize, connect and continually update a wide variety data in PharmaPendium. Get the latest content statistics for PharmaPendium.
PharmaPendium includes safety, PK, MET, efficacy, activity, FAERS and drug data, as well as approval packages and documents from the FDA and EMA.
PharmaPendium and Embase combined empower you to find additional indications for drug repurposing of unapproved or approved drugs. With the breadth of data in Embase and PharmaPendium, you can find relevant clinical studies and data to predict the requirements of clinical trial design and to mitigate risk. In addition to data on approved drugs in PharmaPendium, Embase provides information on unapproved drugs. Embase covers more than 8,500 scientific journals and millions of abstracts from 11,500 conferences worldwide.
Get comprehensive data and innovative tools to analyze drug safety, deliverability and efficacy
